ABSTRACT
Sanitization is a protective and strategic approach to contain SARS-CoV2 dissemination. As there is no feasible way to deal with the new COVID-19 pandemic, sanitization has a key role to play. A modified method to reduce the spread of the virus by constructing a fogging room with a disinfectant and a base fluid mixture has been examined. The nanometer-sized corona in micron-sized cough droplets can quickly reach inaccessible areas when infection is present. Therefore, efficient spray and jet method should be used to disinfect certain inaccessible surfaces. A stand-alone photovoltaic (PV) system represents a pollutant-free and cost-effective solution to the stated issue. The present study aims to design sizing of a small-scale solar panel -powered mobile cleaning and disinfection chamber system for coronavirus in Remote Locations. The objective is to evaluate the sizing of the PV system to power the disinfection chamber system that is used to eliminate the spread of the virus at a constant daily load profile. The system is composed of a fogging room, water tank, PV panels, and storage batteries. The disinfection chamber system requires an energy of approximately 218 Wp with about 38 hours of battery storage that can operate the system continuously after the sunset. Powering a mobile cleaning and disinfection chamber system with PV panels has plenty of advantages, including free-maintenance, easy installation, and energy saving. © 2023 AIP Publishing LLC.
ABSTRACT
This work was performed to examine an idea about full chelation of Iron (Fe) by well-known favipiravir (Fav) as a possible mechanism of action for medication of COVID-19 patients. To this aim, formations of Fe- mediated dimers of Fav were investigated by performing density functional theory (DFT) computations of electronic and structural features for singular and dimer models. The results indicated that the models of dimers were suitable for formation, in which two cis (D1) and trans (D2) models were obtained regarding the configurations of two Fav counterparts towards each other. Energy results indicated that formation of D1 was slightly more favorable than formation of D2. Molecular orbital features affirmed hypothesized interacting sites of Fav for Fe-mediated dimers formations, in which atomic charges and other molecular orbital related representations affirmed such achievements. Moreover, detection of such dimer formation was also possible by monitoring variations of molecular orbitals features. As a consequence, formations of Fe-mediated dimers of Fav could be achievable for possible removal of excess of Fe as a proposed mechanism of action for Fav in medication of COVID-19 patients.